The success rate world wide is %87 for Ileral Interposition Surgery. Diabetes disease, which is one of the most common diseases in the world and continues to increase day by day, can be eliminated with "Ileal Interposition" surgery, which has been preferred for 10 years.
Diabetes Surgery (Ileal Interposition) is a digestive system surgery that provides the rearrangement of metabolism. This surgery is the type of surgery that controls Type 2 diabetes and is applied laparoscopically. In other words, it is a surgical method that controls blood sugar without using insulin.
Basically ,diabetes surgery (Ileal Interposition) is the displacement of the lower part of the small intestine and the initial part. The main target of this process is to increase the secretion of a hormone called GLP-1 from the small intestine. GLP-1 is a hormone that increases the effect of the sugar balancing hormone and stimulates its production in the pancreas. GLP-1 is secreted from the last part of the small intestine.
In diabetes surgery (Ileal Interposition), not only the end of the small intestine is displaced.In addition, the storage part is removed from the edge of the stomach in order to create other hormone changes to strengthen the effect of diabetes surgery. The "hunger" hormone called "ghrelin" is secreted from this removed part of the stomach. The task of the Ghrelin hormone is to stimulate the feeling of hunger and enable us to eat. With the removal of the region secreted from the stomach during diabetes surgery, especially in Type 2 Diabetes, the hormone levels of ghrelin increase to very low levels.
The purpose of removing part of the stomach during diabetes surgery is not to decrease the volume of the stomach. The aim is to reduce the secretion of the hormone ghrelin, which triggers the feeling of hunger. Therefore, in the Ileal Interposition surgery, a larger stomach is left than the tubing of the stomach performed as a morbid obesity surgery. The reason that allows patients to eat less is the hormonal new regulation.
For these reasons, diabetes surgery is an anatomically advanced digestive system surgery, but it is exactly an endocrine surgery procedure in terms of its mechanism of action. In Ileal Interposition surgery applied for diabetes, each step has a hormonal target. These goals are evaluated for each patient, taking into account a wide variety of factors and, if necessary, changes are made according to the patient's condition.
The metabolic effect of ileal interposition surgery is mainly due to hormonal changes that result from moving the small intestine up. As a result of these hormonal changes, the feeling of hunger is suppressed in patients. Particularly, the tissue resistance in muscle tissue and adipose tissue is broken and the capacity of the pancreas to produce sugar hormone is increased. This effect is called “neuro-endocrine brake”. Refers to a kind of neural and hormonal braking system that originates from the intestines and acts on the brain. Therefore, there is no need for serious caloric restrictions on patients.
Who can undergo this surgery?
This surgery can be performed in suitable patients who have uncontrolled type 2 diabetes, insufficient cell reserve in the pancreas, lack of autoantibodies and risk of permanent organ damage occurance.
Also the patient's BMI should be equal to or more than 25 in order to perform this surgery.
A 2-month light diet is applied after the operation. The purpose of this is to prevent leakage in the stomach and intestine connections. The purpose of the surgery is to get rid of diabetes and the patient can do everything. With this surgery, diabetes can be brought under control in 1 week to 2 months. Since you do not even have pain from the day after the surgery, you can live and move like normal healthy people. Working patients can return to their work life within a week.